Scott Sibole

Scientific Interests and Work

Orthopedic biomechanics, continuum mechanics, scientific image analysis, and machine learning.

Dr. Sibole’s research interests include computational modelling and simulation in orthopedic biomechanics, software development for the analysis of scientific and medical images, and the application of numerical methods and machine learning to problems in engineering and health.


Dr. Scott Sibole earned his Ph.D. in Biomedical Engineering from the University of Calgary in 2022. His graduate research focused on the development of software tools for the analysis of articular cartilage tissue and cellular deformation from 3-D microscopic imaging. These tools allow for the investigation of changes in the cellular mechanical environment resulting from physics occurring at higher spatial scales. Additionally, he utilized computational modelling and simulation to further investigate these multiscale mechanics. While completing his Ph.D. he joined a small consulting group that developed custom software solutions to diverse problems in industry and academia. These included applications ranging from minimizing energy usage for the heating and cooling of large commercial buildings to constructing machine learning models to rapidly screen candidate molecules for pharmaceutical treatment. Dr. Sibole joined the Applied Sciences Laboratory, Institute for Shock Physics at Washington State University in April 2024.


Ph.D. (Biomedical Engineering), 2022, University of Calgary, Calgary, Alberta

M.S. Biomedical Engineering, 2016, University of Calgary, Calgary, Alberta

B.S. Biomedical Engineering, 2007, University of Akron, Akron, Ohio

Honors and Recognition

  • Graduate Student Research Excellence Award, 2023, University of Calgary Schulich School of Engineering
  • Killam Doctoral Scholarship, 2017, Izaak Walton Killam Memorial Fund
  • Alberta Innovates Health Solutions Graduate Student Scholarship, 2014, Alberta Innovates Health Solutions

Representative Publications

  1. S. C. Sibole, E. K. Moo, S. Federico, and W. Herzog, “The Protective Function of Directed Asymmetry in the Pericellular Matrix Enveloping Chondrocytes,” Annals of Biomedical Engineering, pp. 1–17, 2022.
  2. S. C. Sibole, E. K. Moo, S. Federico, and W. Herzog, “Dynamic Deformation Calculation of Articular Cartilage and Cells Using Resonance-Driven Laser Scanning Microscopy,” Journal of Biomechanical Engineering, v. 145, no. 2, 021005, 2022.
  3. E. K. Moo, S. C. Sibole, S. K. Han, and W. Herzog, “Three-Dimensional Micro-Scale Strain Mapping in Living Biological Soft Tissues,” Acta Biomaterialia, vol. 70, pp. 260–269, 2018.
  4. S. C. Sibole, S. Maas, J. P. Halloran, J. A. Weiss, and A. Erdemir, “Evaluation of a Post-Processing Approach for Multiscale Analysis of Biphasic Mechanics of Chondrocytes,” Computer Methods in Biomechanics and Biomedical Engineering, vol. 16, no. 10, pp. 1112–1126, 2013.
  5. S. C. Sibole and A. Erdemir, “Chondrocyte Deformations as a Function of Tibiofemoral Joint Loading Predicted by a Generalized High-Throughput Pipeline of Multi-Scale Simulations,” PLoS One, vol. 7, no. 5, e37538, 2012.